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The molecular immunology group is headed by Prof. Omer Dushek & Prof. P. Anton van der Merwe. We study how important white blood cells called T cells control immune responses. These responses can be helpful when directed towards infections and cancers but can also be unhelpful leading to autoimmunity, allergy, and transplant rejections.
Our research is focused on understanding how T cells make these critical response decisions. We aim to develop a quantitative understanding of how signals from many surface receptors are integrated into a T cell response decision. We use our findings to improve existing immune therapies and to develop new ones.
We are based at the Sir William Dunn School of Pathology at the University of Oxford and collaborate with many research groups across the planet.
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